Today, science-infused skincare is more than just a trend, but a necessity. Madeca Derma is an innovative brand. They are a frontrunner in sustainable, science-infused beauty. Madeca Derma’s innovative products are backed by clinical technology and a commitment to natural ingredients, which make them a top choice for those seeking premium skincare solutions. With over 50 years of global pioneering in the skincare industry, this luxury brand is transforming the landscape of beauty with their cutting-edge, clinically-backed treatments.

Madeca Derma Skincare Revitalizing
The Genesis of Madeca Derma
Madeca Derma epitomizes the marriage of advanced biotechnology and natural beauty. This premium skincare line prides itself on harnessing botanicals through rigorous scientific processes to deliver unparalleled skin benefits. By focusing on clean, natural ingredients and eschewing harsh chemicals and synthetics, Madeca Derma ensures each product is as pure as it is effective.

Madeca Derma Skincare Brightening Serum
A Commitment to Clean Beauty
Madeca Derma is dedicated to an uncompromising commitment to ingredient integrity. By working directly with harvesters, the brand meticulously sources ingredients, considering factors like climate and soil quality. This dedication ensures that every product is free from toxic ingredients such as parabens, sulfates, and artificial fragrances.
Innovative Collections for Radiant Skin
The brand’s diverse range of collections caters to various skin needs. Among its offerings are soothing botanical treatments and groundbreaking skin-derived microbiome serums. The latter is particularly noteworthy for its revolutionary approach to anti-aging.

Madeca Derma Skincare Serums
The Microbiome Revolution
“Just as our gut is protected by helpful bacteria, our skin is shielded by tiny microorganisms that strengthen the skin barrier,” explains Colleen Baren, Head of Sales at Besselco. “Our Microbiome Ampoules contain the world’s first ‘elasticity-biome’ extracted from 71 billion CFU (Colony-forming Unit) of Epidermidis Bacteremia keratin found in our skin. This brings a whole new meaning to the word ‘anti-aging’.”
Why Madeca Derma Stands Out
What sets Madeca Derma apart is its relentless pursuit of quality and sustainability. The brand doesn’t take shortcuts, ensuring that each naturally-derived ingredient is preserved for maximum efficacy. Their science-driven approach means that every product not only meets but exceeds industry standards, offering consumers healthier, more radiant skin.

Coleen Baren, Head of Sales at Besselco
We wanted to know more and had some questions for Colleen Baren:
LAsThePlace.com: What inspired the creation of Madeca Derma and what drives its ongoing innovation?
Colleen Baren: With over 50 years of history rooted in medicinal heritage, we are focused on providing innovative healing skincare. Our product portfolio contains cutting-edge innovation. Korea’s medical heritage, powered by nature and developed by pharmaceutical companies, leads the global beauty curve. This is especially true in skincare. Madeca Derma, developed by Korean pharmaceutical leader Dongkook Pharmaceuticals, is unleashing innovation that is years ahead of the global market.
LATP: Can you explain how you use advanced technology to harness and preserve the benefits of botanicals in your products?
CB: Our dedication to purity and efficacy of ingredients found in nature, has led us to open a facility in Korea for the sole purpose of Natural Plant Extraction. The facility opened in 2018.
We find the best features without damaging the properties of the ingredients rather than finding a fast path. Each of the ingredients are methodically extracted and preserved for your skin’s benefit.
- +50 years of skin science expertise
- Optimal blending ratio creating patented formulations for enhanced efficacy
- Industry leading manufacturing process – Natural Extraction Plant opened 2018. Including patented extraction technologies.
LATP: How does Dongkook Pharmaceutical’s expertise in medicine influence the quality and safety of Madeca Derma skincare?
CB: Developed by Dongkook Pharmaceutical, a leading Korean company, our brand reflects the value of clean, sustainable beauty. The legacy continues today with time-honored natural ingredients that are clinically validated through technology. We use the healing power of plants transformed into advanced skincare science, unleashing their vital life force for natural skin restoration. We are committed to using only ingredients that benefit the health of the skin, minimizing harsh chemicals and synthetic ingredients.
LATP: In what ways does Madeca Derma bring a new meaning to luxury skincare with its focus on sustainability and natural ingredients?
CB: Our advanced biotechnology sets the stage for a luxurious at-home experience that rivals clinical medspa treatments, all while prioritizing the health of your skin and the environment. Powered by Science, Activated by Nature from a Pharmaceutical vs. a Cosmetics company results in clinically proven healing and prevention of our skin, not just reactionary care.
LATP: What are the biggest scientific advancements Madeca Derma has made in skincare involving the skin’s microbiome?
CB: Our product portfolio contains cutting-edge innovation. Our ground-breaking powerhouse is the Madeca Microbiome Ampoule collection. It is a 1st global launch, powered by advanced biotechnology. Just as our gut is protected by helpful bacteria, our skin is protected by tiny micro-organisms that shield and strengthen the skin barrier. This patented Microbiome line addresses skin concerns, such as elasticity, hydration, sensitivity and brightening. The ‘living’ microbiome in each ampoule, nestled in hyaluronic acid, resets our skin’s microbiome, healing and strengthening our skin’s barrier. Each product has an active microbiome scientifically formulated with patented, natural ingredients to restore our skin microbiome to good health.
In addition to the patented ingredients, Madeca MicroBiome Ampoules contain a patented “splicing” technology within its delivery system. The delivery environment allows for the microbiome actives to “go home” to their original biome ball state after every use, ensuring efficacy and potency with every application. These living microorganisms know they are stronger as a community versus individuals.
LATP: How do Madeca Derma products support the skin’s natural microbiome, and why is this important for long-term skin health?
CB: Skin Microbiome health is an important piece of our total body health. Our Microbiome products are focused on balancing, restoring and rebuilding our skin microbiome to ensure our barrier to external aggressors is at its’ optimal health.
Keep in mind our skin is our largest organ and requires attention. Skin conditions can influence the overall health of our body inside and out. It’s never too late to heal, protect and love our skin!
Our hero in the line is the Madeca Elastic MicroBiome. The Elastic MicroBiome contains ingredients naturally found in our skin, thus creating a moment of familiarity as the ‘younger’, healthier skin cells in the Elastic Microbiome Ampoule join our ‘aging’ skin cells, resetting the skin’s barrier to a youthful position.
The innovation is nothing like you’ve seen. “If Apple created a skin care line, this would be it,” says Naturally Danny Seo.
Double the elasticity in your skin with our patented microbiome toner. Containing 30 billion CFU of high-potency microbiome that will leave your skin glowy and flexible by balancing the skin’s microbiome level.
Important things to consider when selecting skin care products/routine:
While trends and buzz ingredients catch our attention and can influence our approach, skin care is truly an individual experience. I’d recommend researching ingredients and their source; nature vs. lab; pharma vs. cosmetic; science vs. marketing. Lean on nature and ingredients that compliment your individual ecosystem, based in science and rooted in a healing heritage.
Patents and clinicals in skin care are key in the validation of ingredients, formulation and results. Skin care is an investment in both time and money, proof of efficacy can ensure ROI (results of investment)! Heal your skin, don’t hide it.
Don’t get stuck in a rut of a skincare routine. While we all have our “fav” products or types of products in our routine, remember our skin is continuously evolving depending on external aggressors. What your skin needs at this moment, may be different in the upcoming months. Listen to your skin and adjust your skin care routine accordingly to create the healthiest you.
The rest of our Madeca Derma portfolio isn’t short on patented innovation, clinicals or nature either. We have a Squeeze collection powered by vitamins from fruits and vegetables to boost our skin’s vibrancy; a gentle, vegan, Botanical line to cleanse and soothe; and our Revitalizing line to bolster moisture powered by our proprietary TECA from the Centella Asiatica plant.
Thank you Colleen! Experience the future of skincare with Madeca Derma for yourself, where science and nature blend seamlessly to bring you the best in beauty innovation. Go to Madeca.com to check out all their innovative skincrae products.


